HISTOLOGY: PRACTICE 5

SINGLE BEST OPTION SERIES

         INSTRUCTION: SELECT THE SINGLE BEST OPTION

1.               Generally, connective tissues originate from:
   a.       Yolk sac
   b.      Mesenchymal cells
   c.       Cloaca
   d.      Glycosaminoglycans
   e.      Endoderm of embryos
   2.       Which of the following is incorrect about plasma cells?
   a.       They are large ovoid cells with basophilic cytoplasm
   b.      Their nuclei is commonly described as having a clock-face appearance
   c.       They are derived from T-lymphocytes
   d.      They synthesize antibodies
   e.      They are few in connective tissues and have short half-life
   3.       Which of the following is incorrect about Hematoxylin and Eosin?
   a.       Hematoxylin stains the nucleus of cells and other acidic structures
   b.      Eosin stains the cytoplasm of cells and collagen pink
   c.       Eosin is an acidic dye
   d.      Hematoxylin stains the basophilic components of tissues
   e.      None of the above
   4.       Which of the following is incorrect about using hybridization in making histological diagnosis?
   a.       Hybridization is the binding between two single strands of nucleic acids that recognize each other if the strands are complementary
   b.      Hybridization allows for the nonspecific identification of sequences of DNA  or RNA
   c.       In in situ hybridization, the tissue section, cultured cells or smears or chromosomes of squashed mitotic cells must first be heated to separate the double strands of their DNA
   d.      Northern blotting for RNA is an example of application of hybridization
   e.      None of the above
   5.       The following are specializations of cell surface except:
   a.       Microvilli
   b.      Flagella
   c.       Golgi apparatus
   d.      Cilia
   e.      Stereo-cilia
   6.       Based on how secretory products leave the cells, glands can be classified as the following except:
   a.       Paracrine
   b.      Merocrine
   c.       Holocrine
   d.      Apocrine
   e.      None of the above
   7.       Connective tissue cells include the following except:
   a.       Fibroblast
   b.      Neural crest cells
   c.       Adipose cells
   d.      Osteoblasts 
   e.      Mast ells
   8.       Which of the following is incorrect about leucocytes?
   a.       The normal connective tissues contain leucocytes
   b.      They migrate from the blood vessels into tissues by pinocytosis
   c.       They do not return to the blood after residing in connective tissues
   d.      Killed neutrophils during inflammation are usually mopped up by macrophages
   e.      None of the above
   9.       Steps in preparing tissues for microscopic examination include the following except:
   a.       Fixation
   b.      Bombarding
   c.       Embedding
   d.      Staining
   e.      Counterstaining in immunocytochemistry
   10.   Concerning methods histology and cell biology, which of the following is incorrect?
   a.        Transmission electron microscopy uses thin specimen sections reveals details of the cell’s interior
   b.      Scanning electron microscopy provides a high resolution view of thee cell surface and environment
   c.       Autoradiography uses radioactive isotopes to localize substances within cells
   d.      Staining is used in light and electron microscopy to decrease the contrast of specimen structures
   e.      Artifacts may appear to be true histological features 
   
   
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